Peranan Statin Dalam Memperbaiki Fungsi Paru pada Penyakit Paru Obstruktif Kronik (PPOK)

Abstract

Chronic obstructive pulmonary disease (COPD) is a disease state characterized by airflow limitation that is not fully
reversible and a global health problem with an increasing incidence. Latest pathogenesis states that inflammation
occurs in COPD is not just limited to the airway and parenchymal lung disease, but a systemic inflammation involving
other systems, especially the cardiovascular system. Therefore, the approach to COPD therapy currently includes two
aspects, suppression of lung inflammation and systemic diseases. One of the the therapeutic agent that may affect
both aspects are statin.