Luaran Kehamilan Dengan Sistemik Lupus Eritematosus

Abstract

Systemic lupus erythematosus often abbreviated to SLE or lupus, is a systemicautoimmune disease (or autoimmune
connective tissue disease) that can affect any part ofthe body. As occurs in other autoimmune diseases, the immune
system attacks the body’scells and tissue, resulting in inflammation and tissue damage. It is a type IIIhypersensitivity
reaction caused by antibody-immune complex formation. Women with lupus are at risk for various complications of
pregnancy, and those with antiphospholipid antibodies may have an increased risk of miscarriage. Systemic lupus
erythematosus increases the risk of spontaneous abortion, intrauterine fetal death, preeclampsia, intrauterine growth
retardation, and preterm birth. The outcome for both mother and child is best when systemic lupus erythematosus has
been under good control for at least six months before pregnancy and when the kidney disease is in remission.