Terapi Intravenous Immunoglobulin (IVIG) pada Pasien Covid-19 di Intensive Care Unit (ICU)

Ferianto Ferianto, Suwarman Suwarman, Sobaryati Sobaryati

Abstract

Intravenous immunoglobulin (IVIG) is a plasma derivative product that can provide passive immune protection against various pathogens. IVIG was given to COVID-19 patients who are seriously and critically ill. In this case report, a 43-year-old male patient who has been confirmed with COVID-19 is admitted to the COVID-19 ICU. The patient complains of tightness, coughing and weakness. The examination found decreased SpO2, hypertension and Chest X-ray revealed bilateral bronchopneumonia. On the first day the patient was given antiviral remdesivir 200mg drip IV/3 hours, amlodipine 1x 5mg, codeine 3x10 mg, combivent 3x1, furosemide, and albumin 25% 2 kolf. On days two to five patients were given antiviral remdesivir 100mg drip IV/3 hours, IVIG, namely Gamaras 5 flash, heparin 25,000 units. On the tenth day of treatment in the ICU, the patient’s complaints had decreased. On the eleventh day the patient had no complaints and the patient’s vital signs concluded that the problem was resolved.

Keywords

COVID-19, ICU, Intravenous immunoglobulin

Full Text:

PDF

References

Wiersinga WD, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (covid-19): a review. J Am Med Assoc 2020; 324(8):782–793.

Singhal T. A review of coronavirus disease-2019 (COVID-19). Indian J. Pediatr 2020; 87(4): 281–286.

Satgas penanganan COVID-1. Peta sebaran COVID-19. 2020. Tersedia pada: https://covid19.go.id/peta- sebaran.

Xie Y, Cao S, Wang R. Effect of regular intravenous immunoglobulin therapy on prognosis of sever pneumonia in patients with COVID-19. J Infect 2020;81(2):318–356.

Nguyen AAA, Habiballah SB, Platt CD, Geha RS, Chou JS, Mcdonald DR. Immunoglobulins in the treatment of COVID-19 infection: proceed with caution. Clin Immunol 2020;216:1-4.

Lanza M et al. Successful intravenous immunoglobulin treatment in severe COVID-19 pneumonia. IDCases 2020; 21:e00794.

Tzilas V, Manali E, Papiris S, Bouros D. Intravenous immunoglobulin for the treatment of COVID-19 : a promising tool. Respiration 2020; 99:1087–1089.

Cao W et al. High-dose intravenous immunoglobulin as a therapeutic option for deteriorating patients with coronavirus disease 2019. Open Forum Infect Dis 2020;7(3):1–6.

Tabarsi P et al. Evaluating the effects of intravenous immunoglobulin (IVIG) on the management of severe COVID-19 cases: a randomized controlled trial. Int Immunopharmacol 2020;9:107205.

Refbacks

  • There are currently no refbacks.