Profil Demografi dan Klinis Pasien Dermatitis Atopik: Studi Deskriptif di Indonesia

Alida Widiawaty, Wresti Indriatmi, Wisnu Jatmiko, Endi Novianto, Hendra Gunawan, Aria Kekalih, Pramudita Satria Palar, Adenia Zanna

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disorder that frequently presents in childhood and may persist into adulthood. Globally, AD affects up to 20% of children and approximately 10% of adults, representing a major contributor to the global disability burden of skin diseases. This study aimed to describe the demographic and clinical characteristics of AD patients, including age and sex distribution, history of allergen/irritant exposure, infections, disease duration, and lesion distribution. A descriptive study was conducted using medical record review and direct anamnesis from patients clinically diagnosed with AD by dermatology, venereology, and aesthetic specialists, based on the Hanifin and Rajka criteria. Data were analyzed descriptively. The study included patients aged 0–65 years, with the largest group being infants to early adolescents (0–16 years; 43.67%). The sex distribution was nearly balanced. Only 4.5% reported a history of specific allergen/irritant contact. Concurrent infections were present in 12.7% of patients (predominantly dental/gum infections), while 87.3% had no co-infections. Most patients (89.1%) experienced symptoms for more than four weeks. The most common lesion sites were the lower limbs (20.7%), upper limbs (14.9%), and flexural areas (antecubital: 9.4%, popliteal: 6.3%, neck: 5.4%). AD patients exhibited a broad age range with a significant proportion in the infant-to-early adolescent group, predominance of lesions in the extremities and flexural regions, and a chronic disease course. These findings highlight the need for long-term management strategies and comprehensive care for AD patients across all age groups, including adults and the elderly

Keywords

atopic dermatitis; epidemiology; lesion distribution; precipitating factors

Full Text:

PDF

References

Huang A, Cho C. Atopic dermatitis: early treatment in children. Curr Treat Options Allergy. 2017;4:355-69.

Weidinger S, Beck LA, Bieber T, Kabashima K, Irvine AD. Atopic dermatitis. Nat Rev Dis Primers. 2018;4(1):1.

Tian J, Zhang D, Yang Y, Huang Y, Wang L, Yao X, et al. Global epidemiology of atopic dermatitis: a comprehensive systematic analysis and modelling study. Br J Dermatol. 2023;190:55-61.

Kelly KA, Balogh EA, Kaplan SG, Feldman SR. Skin disease in children: effects on quality of life, stigmatization, bullying, and suicide risk in pediatric acne, atopic dermatitis, and psoriasis patients. Children (Basel). 2021;8:1057.

Kolb L, Ferrer-Bruker SJ. Atopic dermatitis. Treasure Island (FL): StatPearls Publishing; 2025 [Internet]. [Diakses 7 Agustus 2025]. Tersedia: https://www.ncbi.nlm.nih.gov/books/NBK448071/

Abuabara K, Yu AM, Okhovat JP, Allen IE, Langan SM. The prevalence of atopic dermatitis beyond childhood: a systematic review and meta-analysis of longitudinal studies. Allergy. 2018;73(3):696-704.

Wu W, Chan TC, Chu C. Asian type atopic dermatitis. CosmoDerma. 2022;2:48.

Meledathu S, Naidu MP, Brunner PM. Update on atopic dermatitis. J Allergy Clin Immunol. 2025;155(4):1124-32.

Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol. 1980;60(Suppl 92):44-7.

Chan LN, Magyari A, Ye M, Al-Alusi NA, Langan SM, Margolis D, et al. The epidemiology of atopic dermatitis in older adults: a population-based study in the United Kingdom. PLoS One. 2021;16(10):e0258213.

Park JH, Prochnow T, Chang J, Kim SJ. Health-related behaviors and psychological status of adolescent patients with atopic dermatitis: the 2019 Korea Youth Risk Behavior Web-Based Survey. Patient Prefer Adherence. 2023;17:739-47.

Siegfried EC, Hebert AA. Diagnosis of atopic dermatitis: mimics, overlaps, and complications. J Clin Med. 2015;4(5):884-917.

Criado PR, Miot HA, Bueno-Filho R, Ianhez M, Criado RFJ, de Castro CCS. Update on the pathogenesis of atopic dermatitis. An Bras Dermatol. 2024;99(6):895-915.

Ibekwe PU, Ekop E, Otu T, Bassi P, Ukonu BA. Atopic dermatitis in adults: prevalence, clinical pattern, and contact sensitization. Explor Asthma Allergy. 2024;2:450-60.

Fyhrquist N, Yang Y, Karisola P, Alenius H. Endotypes of atopic dermatitis. J Allergy Clin Immunol. 2025;156(1):24-40.e.

Oliveira ADT, Sodré CS, Ferreira DC, Abad ED, Saintive S, Ribeiro M, et al. Oral aspects identified in atopic dermatitis patients: a literature review. Open Dent J. 2018;12:424-34.

Yue C, Zhou H, Wang X, et al. Atopic dermatitis: pathogenesis and therapeutic intervention. MedComm. 2024;5(3):e392.

Wang V, Boguniewicz J, Boguniewicz M, Ong PY. The infectious complications of atopic dermatitis. Ann Allergy Asthma Immunol. 2021;126(1):3-12.

Stigeni L, Belloni FA, Baiardini I, Hansel K, Moretti D, Cipriani F. Atopic dermatitis and patient perspectives: insights of bullying at school and career discrimination at work. J Asthma Allergy. 2021;14:919-28.

Schäbitz A, Eyerich K, Garzorz-Stark N. So close, and yet so far away: the dichotomy of the specific immune response and inflammation in psoriasis and atopic dermatitis. J Intern Med. 2021;290(1):27-39.

Refbacks

  • There are currently no refbacks.