Gambaran Pemakaian Antibiotika Setelah Implementasi Pedoman Pemakaian Antibiotika di Bangsal Kenanga RSUD Arifin Achmad Provinsi Riau Periode Juni-Agustus 2016

Abstract

Implementation of antibiotic guideline as part of “Antibiotic Stewardship Programs (ASPs)”, can both optimize the
treatment of infections and reduce adverse events associated with antibiotic use, antibiotic resistance and saving
hospitals funds. This study describes quantitative and qualitative evaluation and cost of antibiotic use after
implementation of antibiotic guideline in Kenanga ward Arifin Achmad General Hospital.This research was a descriptive
prospective study. All inpatients given antibiotic in Kenanga ward from June – August 2016 were evaluated. The
quantitative antibiotic use was calculated with DDD (daily define dose) meanwhile Gyssens method was used to
calculate qualitative of antibiotic use. There were 137 patients fulfilled inclusion criteria. The most antibiotic used
were ceftriaxone, ciprofloxacin, levofloxacin, meropenem and cefoperazone. There was increased consumption of
quinolone class antibiotics. The highest DDD’s antibiotic was ceftriaxone (96.5). Qualitative measurement showed
that rational antibiotic (Gyssens category 0) was 46%, irrational (Gyssens category I - IV) was 35 % and no indication
of antibiotic use (Gyssens category V) was 19%. The total cost of antibiotics in this period were Rp 41,444,766.After
antibiotic guideline implementation, we found that the most frequent antibiotic was ceftriaxone and irrational use of
antibiotic was still high.