Hubungan Respon Imun Humoral dengan Derajat Trombositopenia pada Pasien Demam Berdarah Dengue

Abstract

The correlation between humoral immune response with the level of of thrombocytopenia on dengue hemorrhagic
fever patient The aim of this study was to know the correlation between humoral immune response with the level of of
thrombocytopenia on dengue hemorrhagic fever patient. This is a cross sectional analytical study on internal inpatients
of AwalBros Pekanbaru Hospital in August-November 2008. Population was all internal inpatients of AwalBros Pekanbaru
Hospital with working diagnosis dengue hemorrhagic fever. There were 4 pattern of anti Dengue antibody : IgG-/IgM,
IgG-/IgM+, IgG+/IgM-, IgG+/IgM+. Most of patients with IgG+/IgM+ and have secondary dengue infection Those
result were analyzed by Friedman statistical test. There isn’t a significant correlation between the level of
thrombocytopenia and anti dengue antibody. It show that there wasn’t a direct correlation between them. It could be
due to a cross reaction between anti dengue antibody with thrombocyte (autoantibody).