Compliance Pengguna Antihipertensi di RSUP DR. SARDJITO Yogyakarta (Periode Juli 2006- Juni 2009)

Abstract

Hypertension is the second largest of the 10 diseases on an outpatient at a hospital in Indonesia. The poor compliance
to therapy of hypertension is a major cause of uncontrolled blood pressure. The aim of this study is to determine
compliance antihypertension on patient at DR. Sardjito hospital Yogyakarta. This study was designed with a
retrospective cohort study design using a database of participants claimed prescribing health insurance (ASKES) in
the DR. Sardjito hospital using antihypertensive drugs. Compliance measured with medication possession ratio (MPR).
Data was analysed by chi- square and logistic regression statistic. From 8.011 patients, compliance of antihypertensive
drugs during the first year is 7,6%. Analysis for compliance showed that the type of antihypertensive diuretics are
more compliance compare with angiotensin II receptor blockers, ACE inhibitors, calcium channel blockers and beta
blockers. Combination therapy (20,7%) is more compliance than monotherapy ( 4,1%), as well as drugs administration
1 time a day (8,2%) is more compliance than drug administration 2 times (2,5%) and 3 times a day (3%). The
proportion of compliance in antihypertensive users at DR. Sardjito hospital classified as less good. Compliance
pattern indicates that therapy is not continuous, the longer the use of antihypertensive therapy, the higher the
discontinuous therapy.