Pola Penggunaan Obat pada Pasien Rawat Intensif di RSUD Arifin Achmad Provinsi Riau
Abstract
Critically ill patients in the ICU have organ dysfunction, so they are dependent on sophisticated equipment, monitoring, and therapy. One of the types of treatment in the ICU is medication. The aim is to observe the pattern of drugs in patients in ICU Arifin Achmad General Hospital. This study is a descriptive retrospective with secondary data from medical records. One hundred fifty samples fulfilled the inclusion criteria. Profiled patients in the ICU are male, comparable to female patients (48,7%: 51,3%). The common groupage that is hospitalized in the ICU is 56-65 years old (22,6%). Length of stay is 1-7 days (68%). JKN is the most widely used for payment (72.7%). Eighty-five patients were improved and moved to other rooms (56.7%). The primary cause of admission in ICU is post-surgery (22%). Anti-infection was the most prescribed category of medication (18.8%). The number of prescriptions is 6-10 drugs (40.7%). Parenteral administration is the most common route for administration (85.74%). Duration of therapy is 1-7 days with the number of 1289 drugs (94%).
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Marshall JC, Bosco L, Adhikari NK, et al. What is an intensive care unit? A report of the task force of the World Federation of Societies of Intensive and Critical Care Medicine. J Crit Care 2017 Feb:37:270-276.
Mercadante S, Gregoretti C, Cortegiani A. Palliative care in intensive care units: why, where, what, who, when, how. BMC anesthesiology. 2018 Dec;18(1):1-6.
Zhou S, Skaar DJ, Jacobson PA, Huang RS. Pharmacogenomics of Medications Commonly Used in the Intensive Care Unit. Front Pharmacol. 2018; 9: 1436.
Demir I, Belice T. Polypharmacy: As a Predictive Indicator of Mortality and Length of Stay for Geriatric Patients Charged in ICU. EJMI 2020;4(3):315–319.
Turnbull AJ, Donaghy E, Salisbury, et al. Polypharmacy and emergency readmission to hospital after critical illness: a population-level cohort study. Br J Anaesth. 2021 Feb; 126(2): 415–422.
Payne RA. Polypharmacy and deprescribing. Clinical pharmacology. 2024 Jan; 52(1): 36-39.
Wardani, NLH. Pola polifarmasi di instalasi intensive care unit (ICU) Rumah Sakit Katolik St. Vincentius A Paulo (RKZ) Surabaya selama bulan Juli 2005 sampai dengan Juni 2006 [tesis]. Universitas Surabaya; 2007.
Chan YK, Ng KP, Sim DSN. Pharmacological basic of acute care. Springer; 2015
Salwe KJ, Kalyansundaram D, Bahurupi Y. A Study on polypharmacy and potential drug-drug interactions among elderly patients admitted in department of medicine of a tertiary care hospital in Puducherry. J Clin Diagn Res. 2016;10(2):FC06–10
Tunas IK, Wirajaya MKM. Analisis efisiensi rawat inap di bali royal hospital dengan pendekatan barber johnson. Jurnal manajemen kesehatan yayasan RS. Dr. Soetomo. 2023 Feb; 9(1): 136-150.
Megawati SW, Dewi T, Nurohmat AD, et al. Analisis Mortalitas Pasien di Ruang Intesive Care Unit (ICU). Jurnal medika cendikia. 2020 Des; 7(2): 127-135.
Guidet B, Vallet H, Boddaert J, et al. Merawat pasien kritis berusia di atas 80 tahun: tinjauan naratif . Ann Intensive Care . 2018; 8 ( 1 ):114.
Beil M, Flaatten H, Guidet B, et al. Manajemen multimorbiditas pada pasien lanjut usia: apakah sudah siap untuk pengobatan presisi dalam perawatan intensif? Crit Care . 2021; 25 ( 1 ):330.
Baek H, Cho M, Kim S, Hwang H, Song M, Yoo S. Analysis of length of hospital stay using electronic health records: A statistical and data mining approach. PLoS One. 2018 Apr 13;13(4):e0195901
Soares Pinheiro FGM, Santana Santos E, Barreto ÍDC, Weiss C, Vaez AC, Oliveira JC, Melo MS, Silva FA. Mortality Predictors and Associated Factors in Patients in the Intensive Care Unit: A Cross-Sectional Study. Crit Care Res Pract. 2020 Aug 1;2020:1483827
Aung YN, Nur AM, Ismail A, Aljunid SM. Determining the Cost and Length of Stay at Intensive Care Units and the Factors Influencing Them in a Teaching Hospital in Malaysia. Value Health Reg Issues. 2020 May;21:149-156
Kementerian Kesehatan Republik Indonesia. Keputusan direktur jendral bina upaya kesehatan no. hk.02.04/i/1966/11 tentang petunjuk teknis penyelenggaraan pelayanan intensive care unit (ICU) di rumah sakit. 2011 Juli 26; Jakarta.
Kortelainen S, Curtze S, Martinez-Majander N, Raj R, Skrifvars MB. Acute ischemic stroke in a university hospital intensive care unit: 1-year costs and outcome. Acta Anaesthesiol Scand. 2022; 66: 516–525
Patty VN, Lalenoh DC, Wuisan DD. Profil pasien preeklamsia berat dan eklamsia di ICU dan HCU RSUP Prof. Dr. R. D. Kandou Manado. eClinic. 2016 Jul; 4(2).
Alexiou K, Drikos I, Terzopoulou M, Sikalias N, Ioannidis A, Economou N. A prospective randomised trial of isolated pathogens of surgical site infections (SSI). Ann Med Surg (Lond). 2017 Jul 19;21:25-29.
Khilnani GC, Zirpe K, Hadda V, Mehta Y, Madan K, Kulkarni A, et al. Guidelines for Antibiotic Prescription in Intensive Care Unit. Indian J Crit Care Med. 2019 Jan;23(Suppl 1):S1-S63.
Plasma protein binding of ceftriaxone in critically ill patients: can we predict unbound fractions? J Antimicrob Chemother. 2023 Apr; 78(4): 1059–1065. Tim M J Ewoldt, Soma Bahmany, Alan Abdulla, Anouk E Muller, Henrik Endeman, and Birgit C P Koch.
Dahyot-Fizelier C, Lasocki S, Kerforne T, Perrigault PF, Geeraerts T, Asehnoune K, et. al; PROPHY-VAP Study Group and the ATLANREA Study Group. Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury: a multicentre, randomised, double-blind, placebo-controlled, assessor-masked superiority trial. Lancet Respir Med. 2024 May;12(5):375-385.
Ghimire R, Prasad P, Parajuli S, Basnet R, Lamichhane P, Poudel N, Shrestha PS, Kharel S, Pokharel A, Mudvari A. Potential Drug-drug Interaction among the Patients Admitted in Intensive Care Units of a Tertiary Care Centre: A Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc. 2022 Mar 11;60(247):263-267
Hamidy Y. Significant drug interactions among intensive care unit patients. Ii-indonesian conference on clinical pharmacy. II-Indonesian Conference on Clinical Pharmacy; 2016 Oktober 27-28; Bali, Indonesia.
Kim J, De Jesus O. Medication Routes of Administration. [Updated 2023 Aug 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK568677/
Putri SC. Profil Antibiotik pada Pasien Intensive Care Unit (ICU) di Rumah Sakit Dr. Soedarso Pontianak Periode Januari Juni 2019. Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN. 2019; 4 (1).
Kanno T , Moayyaedi P. Who Needs Gastroprotection in 2020?. Curr Treat Options Gastroenterol. 2020; 18(4): 557–573
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