Pengaruh Pemberian Jus Semangka (Citrullus vulgaris Schard.) Peroral Terhadap Jumlah Spermatozoa Mencit (Mus musculus) Yang Dipapar Asap Rokok

Abstract

Infertility is influenced by many factors, one of them is reactive oxygen species (ROS) containing free radicals. Free
radicals can be neutralized by antioxidants. Watermelon (Citrullus vulgaris Schard.) contains compounds with strong
antioxidant activity so that protect the spermatozoa from the toxic effects of ROS. The purpose of this research was to
determine the effect of watermelon juice to the number of spermatozoa’s mice exposed by cigarette smoke. Its design
was the post test only, while the subjects were 20 male mices, which divided into five groups were baseline, K(-), P1,
P2 and P3. This experimental study lasted for 14 days. On the 15th day, all mice were terminated and the number of
spermatozoa was examinated. One way anova test showed significant differences of spermatozoa count between groups
(p=0,000). Based on post hoc test there were significant differences between group of baseline with K(-) and P1,
between group of K(-) with P2 and P3, and between group of P2 with P1 and P3. This study showed that watermelon
juice increased the number of spermatozoa in mice exposed by cigarette smoke and dose 0.32 ml/day gave the best
effect.